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Provedor de dados:  BABT
País:  Brazil
Título:  Drug interaction with radiopharmaceuticals: a review
Autores:  Bernardo-Filho,Mario
Santos-Filho,Sebastião David
Moura,Egberto Gaspar de
Maiworm,Adalgisa Ieda
Orlando,Margarida Maria de Camões
Penas,Maria Expósito
Cardoso,Valbert Nascimento
Bernardo,Luciana Camargo
Brito,Lavínia de Carvalho
Data:  2005-10-01
Ano:  2005
Palavras-chave:  Drug interaction
Blood constituents
Radiobiocomplexes
Bioavailability
Resumo:  Clinical images are worthwhile in Health Sciences and their analysis and correct interpretation aid the professionals,such as physicians, physiotherapists and occupational therapists, to make decisions and take subsequent therapeutic and/or rehabilitation measures. Other factors, besides the state of the disease, may interfere and affect the bioavailability of the radiopharmaceuticals (radiobiocomplexes) and the quality of the SPECT and PET images. Furthermore, the labeling of some of these radiobiocomplexes, such as plasma proteins, white blood cells and red blood cells, with 99mT, can also be modified. These factors include drugs (synthetic and natural) and dietary conditions, as well as some medical procedures (invasive or non-invasive), such as radiation therapy, surgical procedures, prostheses, cardioversion, intubation, chemoperfusion, external massage, immunotherapy, blood transfusion and hemodialysis. In conclusion, the knowledge about these factors capable of interfering with the bioavailability of the radiobiocomplexes is worthwhile for secure diagnosis. Moreover, the development of biological models to study these phenomena is highly relevant and desirable.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700003
Editor:  Instituto de Tecnologia do Paraná - Tecpar
Relação:  10.1590/S1516-89132005000700003
Formato:  text/html
Fonte:  Brazilian Archives of Biology and Technology v.48 n.spe2 2005
Direitos:  info:eu-repo/semantics/openAccess
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